Bioinformatics
databases and analytics

We are passionate about helping scientists
solve challenges in life sciences
Contact Us

Bioinformatics
databases and analytics

We are passionate about helping scientists
solve challenges in life sciences
Contact Us

Bioinformatics
databases and analytics

We are passionate about helping scientists
solve challenges in life sciences
Contact Us

Bioinformatics
databases and analytics

We are passionate about helping scientists solve challenges in life sciences
Contact Us
Products
We develop databases, tools and algorithms to analyze and visualize large-scale biological data.
CellKb
CellKb
Cell Type Reference Database
version 2.1    21 February 2021
A knowledgebase of manually collected, curated and annotated cell types in multiple species with associated protein-protein interaction networks. CellKb allows users to search through published cell type signatures from selected single-cell and bulk RNA-seq experiments.
CellKb v3.0 contains 24,132 signatures of 1,977 cell types from 9 species extracted from 475 publications with 610,407 associated protein-protein interactions.
CellKb Immune
CellKb_Immune
Cell Type Reference Database of mammalian hematopoietic cell types
version 1.0.1    21 February 2021
A knowledgebase of manually collected, curated and annotated cell types related to the immune system in mouse with associated protein-protein interaction networks. CellKb Immune is a subset of CellKb having the same functionality.
CellKb Immune v1.0.1 contains 1,833 signatures of 203 hematopoietic cell types from mouse extracted from 156 publications with 34,154 associated protein-protein interactions. See Preprint
HitPredict
CellKb
Protein-protein interactions with reliability scores
version 10.0    3 August 2020
An open-source database of experimentally identified protein-protein interactions collected from literature with reliability scores assigned based on the annotations of the interacting proteins. The first version of HitPredict was released in 2005. The HitPredict service and updates are currently provided through Combinatics.
HitPredict v10.0 contains 815,892 protein-protein interactions between 89,685 proteins from 128 species.

About Us
Our goal is to develop reliable databases with advanced search features by extensively curating, integrating, annotating and scoring biological data from literature.
Leadership
Ashwini Patil
Ashwini Patil, PhD.
Founder, CEO
Ashwini has over 20 years of research and development experience in computational biology. She is an expert in the development of bioinformatics methods for the analysis and visualization of diverse biological data. Previously, Ashwini was a Lecturer at the University of Tokyo, Japan.
Ajay Patil
Ajay Patil
Technical Advisor
Ajay has worked for more than 25 years in software development. He is an expert in data processing, system integration, parsing, databases and linux system administration.




News
CellKb v2.1 release
21 February 2021
We have integrated 610,407 protein-protein interactions from HitPredict with CellKb.
Users can now see an interaction network of the query gene list with marker genes of the matching cell type.
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CellKb v2.0.3 release
10 January 2021
A new version of CellKb is up now with cell types from 72 new publications across 9 species. Introducing Consensus Signatures - Search and browse consensus marker gene sets for all cell types calculated from more than 24,000 cell type signatures.
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CellKb Immune preprint
3 December 2020
A preprint describing the functionality and methods in CellKb Immune is out now.
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CellKb Immune v1.0 release
30 October 2020
Today we are annoucing the release of CellKb Immune, a subset of CellKb containing immune cell types from mouse. CellKb Immune is free for academic users.
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CellKb v2.0 release
26 August 2020
Announcing the release of CellKb v2.0 with new marker gene sets, disease annotations, ability to browse the database contents and a FREE academic version.
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HitPredict v10.0 release
3 August 2020
We have released the latest version of HitPredict containing 128 species, 815,892 protein-protein interactions and 89,685 proteins.
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CellKb 1.0 release
26 April 2020
We announce the release of CellKb version 1.0, a knowledgebase of cell types manually collected from literature with deep curation and annotations.
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Get in touch
  Combinatics Inc.
3-2-7-304 Shirokanedai
Minato-ku, Tokyo
Japan 108-0071
  +81-3-4283-6102
  ashwini@combinatics.com